02276naa a2200361 a 450000100080000000500110000800800410001902400540006010000180011424501160013226000090024852012360025765000200149365000230151365000310153665000110156765000170157865000180159565000100161365000250162365000150164865000100166365000100167365000180168365300180170165300180171965300150173765300260175270000210177870000180179970000180181777300790183515220172023-08-03       1985    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/0020-7519(85)90049-92DOI1 aBARGER, I. A.  aRegulation of Haemonchus contortus populations in sheep exposed to continuous infection.h[electronic resource]  c1985  aAbstract: Groups of sheep were infected three times weekly for 15 weeks with infective larvae of Haemonchus contortus at four rates ranging from 600 to 4800 larvae per week. At 3-weekly intervals, sheep from each group were killed for total worm counts after receiving a dose of radiolabelled larvae which enabled a direct measurement of establishment of incoming larvae during the continuing infection. Peak H. contortus burdens were reached between 6 and 9 weeks of infection, and were related to infection rate. In the groups receiving 2400 and 4800 larvae per week, worm numbers then declined rapidly and by the end of the experiment were lower than those in the groups given 600 or 1200 larvae per week. Establishment of incoming larvae was not influenced by infection rate, and declined from 45% in the first 4 weeks of infection to insignificant levels during the final 6 weeks. The proportion of incoming larvae arrested in their development increased as the infection progressed. It was concluded that H. contortus numbers were regulated by development of resistance to infection and by a loss of established worms which was related to the current rate of larval intake, and to the host's previous experience of infection.  aDisease control  aDisease prevention  aGastrointestinal nematodes  aLarvae  aParasitology  aPathogenicity  aSheep  aHaemonchus Contortus  aImunologia  aLarva  aOvino  aParasitologia  aEndoparasitos  aEstablishment  aNematodeos  aPopulation regulation1 aLE JAMBRE, L. F.1 aGEORGI, J. R.1 aDAVIES, H. I.  tInternational Journal of Parasitologygv. 15, n. 5, p. 529-533, Oct. 1985.