00946naa a2200157 a 450000100080000000500110000800800410001910000180006024500550007826000090013352005440014265000130068665000110069965300130071077300650072315218042023-05-15       1990    bl uuuu     u00u1 u    #d1 aRIBBLE, C. S.  aAssessing vaccine efficacy.h[electronic resource]  c1990  aWas the vaccine been laboratory and field-tested in randomized controlled clinical trials? Were the control groups concurrent or historical?How were the trial animals challenged? Was the measure of outcome meaningluf? Were the biology and epidemiology of the disease considered? Was the vaccine assigned randomly? Were blinding techniques used ;to reduce bias? What other potentially important biases are evident? How lilkely was the result a chance finding? What are the differences between the trial animals and animals in your practice?  aVaccines  aVacina  aEficacia  tCanadian Veterinary Journalgv. 31, n. 10, p. 679-688, 1990.