01953naa a2200409 a 450000100080000000500110000800800410001902400320006010000150009224501180010726000090022552008730023465000180110765000190112565000170114465000170116165000210117865000170119965000190121665000100123565000210124565000200126665000150128665000160130165000100131765000180132765000110134565000160135665300130137265300170138565300200140270000160142270000170143870000180145570000200147377300500149315215762025-06-18       1985    bl uuuu     u00u1 u    #d7 a10.1055/s-2007-969457.2DOI1 aJULIEN, J.  aExtracts of the ivy plant, Hedera helix, and their anthelminthic activity on liver flukes.h[electronic resource]  c1985  aAbstract: Three extracts from English or common ivy, Hedera helix, were prepared and tested for their anthelminthic activity both in vitro and in vivo. Saponic complex 60% (CS 60), purified saponic complex 90% (CSP 90) and alpha hederin were evaluated in vitro using the trematodes Fasciola hepatica and Dicrocoelium spp. These same extracts were assayed for their effects on Dicrocoelium in naturally infected sheep. After an exposure of 24 hours in vitro both Fasciola and Dicrocoelium were killed by α-hederin at concentrations of 0.005 and 0.001 mg/ml respectively. When sheep naturally infected with Dicrocoelium were treated p. o. with CS 60 and CSP 90 the worms were eliminated after three doses, one of 500 and two of 800 mg/kg. Alpha hederin was deemed slightly less efficacious at these concentrations. When compared with two reference compounds the authors  aAnthelmintics  aDicrocoeliasis  aDrug therapy  aHedera helix  aMedicinal plants  aPhytotherapy  aPlant extracts  aSheep  aAnti-Helmíntico  aExtrato Vegetal  aFasciolose  aFitoterapia  aOvino  aParasitologia  aPlanta  aTrematódeo  aControle  aEndoparasito  aTherapeutic use1 aGASQUET, M.1 aMAILLARD, C.1 aBALANSARD, G.1 aTIMON-DAVID, P.  tPlanta Medicagv. 51, n. 3, p. 205-208, 1985.