01937naa a2200373 a 450000100080000000500110000800800410001902400330006010000170009324501780011026000090028852009040029765000180120165000110121965000120123065000110124265000150125365000150126865000140128365000170129765000170131465000100133165000190134165000150136065000100137565000170138565300170140265300100141965300190142970000180144870000180146670000190148477300600150315213532023-06-21       1978    bl uuuu     u00u1 u    #d7 a10.1530/acta.0.0890158.2DOI1 aWEISS, T. J.  aEffects of human chorionic gonadotrophin on the release of cyclic AMP and progesterone from the sheep ovary at different stages of the oestrous cycle.h[electronic resource]  c1978  aAbstract: The rate of release of cyclic AMP by sheep ovaries containing a corpus luteum was determined at different stages of the cycle before and up to 60 min after an intra-arterial (ia) injection of 500 IU human chorionic gonadotrophin (hCG). The median cyclic AMP concentration in arterial plasma and of ovarian venous plasma following hCG stimulation was 93.2 and 98.0 pmol/ml, respectively. The ovaries of ewes examined at Days 1 and 2 of the cycle showed no response to hCG, whereas in 2 sheep at Day 3, hCG caused a slight response, and in 13 sheep examined between Days 5-18, hCG caused a marked increase in cAMP release. In 5 of the sheep in which both ovarian veins were cannulated, only the ovary with a corpus luteum responded to hCG with an increased secretion rate of cyclic AMP and progesterone. The results indicate a lack of responsiveness in the newly formed corpus luteum to hCG.  aEndocrinology  aEstrus  aFemales  aHumans  aMetabolism  aPhysiology  aPregnancy  aProgesterone  aReproduction  aSheep  aEndocrinologia  aFisiologia  aOvino  aReprodução  aDrug effects  aOvary  aSecretory Rate1 aJANSON, P. O.1 aPORTER, K. J.1 aSEAMARK, R. F.  tActa Endocrinologygv. 89, n. 1, p. 158-165, Sep. 1978.