01661naa a2200325 a 450000100080000000500110000800800410001902400470006010000200010724500830012726000090021052008030021965000180102265000180104065000120105865000170107065000230108765000140111065000170112465000120114165000190115365000140117265000150118665000100120165000120121165000170122365300200124070000180126077300570127815212852024-01-03       1979    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1677/joe.0.08202872DOI1 aFLINT, A. P. F.  aEpitestosterone in the plasma of the goat during pregnancy and at parturition.  c1979  aEpitestosterone, a product of the metabolism of androstenedione by the caprine placenta in vitro, is present in the plasma of the pregnant goat. The maternal concentrations of both epitestosterone and unconjugated oestrogens (mostly oestradiol-17α) in the blood increased before parturition and dropped post partum. Measurement of arteriovenous differences at term indicated that epitestosterone was secreted by the uterus; its production was not dependent on the presence of corpora lutea. It is suggested that the concentration of epitestosterone (+ androstenedione + oestrogens) in maternal plasma may be used as an indicator of placental C-17,20 lyase activity; the slight rise in the concentration of these compounds prepartum suggests a relatively small increase in flow through this enzyme.  aDexamethasone  aEndocrinology  aFemales  aPharmacology  aPlacental hormones  aPregnancy  aTestosterone  aCaprino  aEndocrinologia  aEstradiol  aFisiologia  aParto  aPrenhez  aReprodução  aEpitestosterone1 aBURROW, P. V.  tJournal Endocrinologygv. 82, n.2, p. 287-291, 1979.