01806naa a2200325 a 450000100080000000500110000800800410001902400390006010000190009924500900011826000090020852009230021765000210114065000160116165000130117765000140119065000140120465000200121865000150123865000100125365000170126365000190128065000150129965000100131465000180132465300240134265300140136670000180138077300820139815209122023-08-02       1987    bl uuuu     u00u1 u    #d7 a10.1016/0020-7519(87)90162-7.2DOI1 aGREGORY, M. W.  aOvine coccidiosisbpathology of Eimeria ovinoidalis infection.h[electronic resource]  c1987  aAbstract: Doses of sporulated oocysts of Eimeria ovinoidalis ranging from 102 to 5 × 106 were given to 25 housed lambs aged between 5 and 13 weeks, most of which had been reared coccidia-free. Some had received an ?immunizing? dose 3?4 weeks earlier. Lambs were killed between 8 and 21 days after inoculation (DAI) and the tissues were examined histologically. Doses higher than 106 caused extensive loss of epithelial cells in the lower jejunum both from the surface and from the crypts at 10 DAI when first-generation meronts were mature. Doses of 103 oocysts or more caused diarrhoea from about 13 DAI in both first and second infections; this was associated with massive invasion of the caecal epithelium by second-generation meronts and gamonts. Destruction of crypt stem cells by these stages led to denudation of the caecal mucosa, resulting in haemorrhagic enteritis, dehydration and delayed healing or death.  aAnimal pathology  aCoccidiosis  aDiarrhea  aDysentery  aEnteritis  aEnteropathogens  aIntestines  aLambs  aParasitology  aSheep diseases  aCoccidiose  aOvino  aParasitologia  aEimeria ovinoidalis  aPatologia1 aCATCHPOLE, J.  tInternational Journal for parasitologygv. 17, n. 6, p. 1099-1111, Aug. 1987.