01893nam a2200241 a 450000100080000000500110000800800410001902400590006010000180011924500700013726000720020752012140027965000100149365000150150365000210151865000170153965000210155665000140157765000120159165000160160365000150161970000170163415208312023-12-01 1965 bl uuuu u00u1 u #d7 ahttps://doi.org/10.3168/jds.S0022-0302(65)88233-92DOI1 aRAMSEY, H. A. aMetabolism of n-butyric by the adult goat.h[electronic resource] aJournal of Dairy Science, v. 48, n. 3, p. 381-390, Mar. 1965.c1965 aAbstract: N-butyrate-1-C14 was injected intravenously into four adult goats. Observations were made on the subsequent incorporation of C14 into liver and muscle glycogen and into various organic acids of blood, taken either from the jugular vein or simultaneously from both the carotid artery and ruminal vein. Though several acids were labeled with C14, ?-hydroxybutyrate exhibited the highest specific activity. Ruminal vein blood contained over twice as much ?-hydroxy-butyrate as did blood from the carotid artery. The concentration of n-butyrate in ruminal vein blood was frequently lower than that of iso-butyrate, even though the ratio of these two acids in the rumen fluid was approximately 7:1. This suggests that ?-hydroxybutyrate is a normal intermediate in the metabolism of n-butyrate absorbed from the rumen and that the rumen epithelium is a major site of this conversion. The lactate of ruminal vein blood was slightly greater in concentration but several times higher in specific activity than lactate of arterial blood. Glucose from both liver and muscle glycogen was labeled with C14 predominantly in Carbons 3 and 4, the ratio of labeling between these two carbons being approximately 1:1. aGoats aMetabolism aRumen epithelium aRumen fluids aRuminant stomach aRuminants aCaprino aMetabolismo aNutrição1 aDAVIS, C. L.