01677naa a2200325 a 450000100080000000500110000800800410001902400270006010000260008724501410011326000090025452007530026365000230101665000200103965000200105965000180107965000130109765000120111065000230112265000170114565000100116265000190117265000100119165000170120165000110121865300150122965300170124470000170126177300730127815206182023-11-16       1976    bl uuuu     u00u1 u    #d7 a10.1071/bi97605452DOI1 aBROWN-WOODMAN, P.D.C.  aDisruption of the matabolism, motility and morphology of spermatozoa by injection of alfa-chlorohydrin into rams.h[electronic resource]  c1976  aEjaculated spermatozoa from rams given intramuscular injections of alfa-chlorohydrin (25mg/kg, daily for 5 days) were studied. Respiratory and glycolytic activity of the spermatozoa was almost entirely suppressed within 1 day and molity had decreased within 4 days of the first injection. Morphology abnormal spermatozoa appeared in ejaculates after 2 weeks. The most common abnormality was an increase in the number of spermatozoa with looped or ben tails. There was litle change in the fructose or amino acid concentration of the seminal plasma. All effects of alfa-chlorohydrin were fully reversible. It is suggested that the imital primary mode of action of alfa-chlorohydrin is to disrupt the metabolism of spermatozoa in the cauda epididymis.  aAlpha-chlorohydrin  aAnimal breeding  aAnimal genetics  aChlorohydrins  aFructose  aGlucose  aOxygen consumption  aPharmacology  aSheep  aSperm motility  aOvino  aReprodução  aSêmen  aAndrologia  aDrug effects1 aWHITE, I. G.  tAustralian Journal Biology Sciencegv. 29, n. 5/6, p. 545-556, 1976.