01905naa a2200313 a 450000100080000000500110000800800410001902400320006010000190009224501570011126000090026852009740027765000180125165000330126965000350130265000170133765000150135465000170136965000100138665000170139665000190141365000150143265000100144765000170145765300170147465300190149165300170151077300640152715205392023-06-21 1979 bl uuuu u00u1 u #d7 a10.1677/joe.0.0800133.2DOI1 aLINCOLN, G. A. aDifferential control of luteinizing hormone and follicle-stimulating hormone by luteinizing hormone releasing hormone in the ram.h[electronic resource] c1979 aAdult Soay rams with low concentrations of gonadotrophins in the circulation as a result of 12 weeks of exposure to long daylangths (16 h light : 8 h darkness) were given small doses (100 ng) of synthetic luteinizing hormone releasing hormone (LH-RH) into the jugular vein two, four or seven times/day for 10 days. Each injection of LH-RH induced a transitory increase in the concentration of LH and testosterone in the plasma, whereas the concentration of FSH showed little immediate change, After repeated treatment with pulses ofd LH-RH, the responses of LH and testosterone became slightly enhanced and the plasma concentration of FSH became permanently raised; these changes were most conspicuous in the animals receiving the most frequent injections. At the endof the study when the injections of LH-RH were stopped, the concentrations of LH and testosterone remained low but the concentrations of FSH continued to be maintained at a high level for at least 24 h. aEndocrinology aFollicle-stimulating hormone aGonadotropin-releasing hormone aPharmacology aPhysiology aReproduction aSheep aTestosterone aEndocrinologia aFisiologia aOvino aReprodução aDrug effects aSecretory Rate aTime Factors tJournal of Endocrinologygv. 80, n.1, p.133-140, Jan. 1979.