01938naa a2200325 a 450000100080000000500110000800800410001910000210006024501690008126000090025052009790025965000210123865000180125965000200127765000170129765000100131465000150132465000140133965000100135365000150136365000170137865300330139565300080142865300190143670000170145570000180147270000130149070000190150377300900152215197072023-03-31       1986    bl uuuu     u00u1 u    #d1 aHENDERSON, K. M.  aEffect on ovulation rate of increasing or decreasing ovarian exposure to follicle stimulating hormone during the preovulatory period in ewes.h[electronic resource]  c1986  aAbstract: Ovine FSH was administered hourly to ewes for 48 h from the initiation of luteolysis. The mean ovulation rates of ewes receiving 2.5 µg FSH/h (2.1 ± 0.2 ovulations/ewe, mean ± s.e.m., n=8) and 5.0 µg FSH/h (6.2 ± 2.0 ovulations/ewe, n=6) were significantly higher (P&lt 0.01) than that of control ewes (1.3 ± 0.1 ovulations/ewe, n=16). Mean plasma concentrations of FSH were also raised above normal by these doses of FSH. Plasma concentrations of FSH were reduced below normal by twice daily administration of steroid-free bovine follicular fluid (bFF) for 48 h from the initiation of luteolysis. As a consequence follicles failed to achieve ovulatory maturity. Large follicles (?5mm diameter) from ewes treated with bFF for 48 h had reduced concentrations of oestradiol-17b in follicular fluid, fewer granulosa cells, and the cells had a reduced ability to metabolise testosterone to oestradiol-17b and to produce cyclic AMP when challenged with FSH or LH.  aFollicular fluid  aGonadotropins  aGranulosa cells  aReproduction  aSheep  aFisiologia  aHormônio  aOvino  aOvulação  aReprodução  aFollicle stimulating hormone  aFSH  aOvulation rate1 aELLEN, R. L.1 aSAVAGE, L. C.1 aBALL, K.1 aMcNATTY, K. P.  tProceedings of the New Zealand Society of Animal Productiongv. 46, p. 157-159, 1986.