01439naa a2200289 a 450000100080000000500110000800800410001910000160006024501940007626000090027052005870027965000200086665000180088665000100090465000140091465000170092865000120094565000190095765000150097665000120099165000170100365300140102070000220103470000280105670000190108477300460110315197002023-06-20 1976 bl uuuu u00u1 u #d1 aWENTZEL, D. aEffect of intrafoetal administration of 4-androstene-3, 17-Dione on circulating maternal oestrogen levels and subsequent reproductive outcome of pregnant Angora does.h[electronic resource] c1976 aTen pregnant Angora goat does were used to investigate the effect of intrafoetal administration of androstenedione on maternal oestrogen levels and pregnancy. In the experimental group 66,7% aborted while no abortions occurred in the control group. Oestrogen levels in androstenedione-treated animals increased abruptly from 29,7 ng ml to 65,5 ng ml while that of control animals remained relatively constant at 25,5 ng ml. It is concluded that the abortifacient effect of excessive androstenedione in the foetal circulation is mediated via an elevated level of maternal oestrogens. aAndrostenedione aEndocrinology aGoats aPregnancy aReproduction aCaprino aEndocrinologia aFisiologia aPrenhez aReprodução aOestrogen1 aWESTHUYSEN, J. M.1 aVAN DER MERWE, J. H. P.1 aVILJOEN, K. S. tAgroanimaliagv. 8, n. 2, p. 39-40, 1976.