02468naa a2200289 a 450000100080000000500110000800800410001902400380006010000210009824502570011926000090037652015030038565000110188865000100189965000090190965000120191870000240193070000170195470000200197170000240199170000170201570000190203270000200205170000200207170000200209177300670211114916172018-05-24       2008    bl uuuu     u00u1 u    #d7 a10.1016/j.mycmed.2008.08.0012DOI1 aTAKAHASHI, J. A.  aIsolation and screening of fungal species isolated from Brazilian cerrado soil for antibacterial activity against Escherichia coli, Staphylococcus aureus, Salmonella typhimurium, Streptococcus pyogenes and Listeria monocytogenes.h[electronic resource]  c2008  aTo study the antimicrobial activity of fungi isolated from Brazilian cerrado soil. Material and methods. A total of 200 fungal strains were isolated from soil samples collected from Serra do Cipó National Park in Brazil. Antibacterial activity against Escherichia coli, Staphylococcus aureus, Salmonella typhimuriu, Streptococcus pyogenes andListeria monocytogenes was screened. Results. Around 67% of the extracts showed activity against at least one of the tested bacteria. Thirteen isolates, selected as the most common species found in the studied soil samples (over 50% of all isolates), were microscopically identified as Chaetomium cupreum, Curvularia senegalensis, Fusarium oxysporum, Penicillium citrinum, Penicillium janthinellum, Penicillium paxilli, Penicillium sclerotiorum, Penicillium simplicissimum, Penicillium waks-manii, Rhizopus stolonifer, Syncephalastrum r acemosum, Trichoderma koningii and Trichoderma reesei. Large scale experiment proved positive antibacterial results for Penicillium sclerotiorum and Penicillium simplicissimum, since bioactive metabolites (sclerotiorin, isochromophilone VI, pencolide and penicillic acid) were recovered from their fermentation in preparative scale. Conclusion. Cerrado soil fungi constitute another important source of antibiotics producing micro-organisms that can be further exploited a s source of lead compounds for anti-infective agents industry. To study the antimicrobial activity of fungi isolated from Brazilian cerrado soil.  aBrazil  afungi  asoil  aCerrado1 aCASTRO, M. C. M. de1 aSOUZA, G. G.1 aLUCAS, E. M. F.1 aBRACARENSE, A A. P.1 aABREU, L. M.1 aMARRIEL, I. E.1 aOLIVEIRA, M. S.1 aFLOREANO, M. B.1 aOLIVEIRA, T. S.  tJournal of Mycologie Médicalegv. 18, n. 4, p. 198-204, 2008.