01603naa a2200241 a 450000100080000000500110000800800410001902400570006010000220011724500990013926000090023852008790024765300110112665300170113765300190115470000220117370000190119570000200121470000140123470000200124870000260126877300670129410466292023-06-29 2003 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1590/S1415-475720030003000082DOI1 aMACHADO, M. B. B. aQTL affecting body weight in a candidate region of cattle chromosome 5.h[electronic resource] c2003 aThe objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle. aBovine aGrowth trits aMicrosatellite1 aALENCAR, M. M. de1 aPEREIRA, A. P.1 aOLIVEIRA, H. N.1 aCASAS, E.1 aCOUTINHO, L. L.1 aREGITANO, L. C. de A. tGenetics and Molecular Biologygv. 26, n. 3, p. 259-265, 2003.