02441nam a2200253 a 450000100080000000500110000800800410001910000200006024500770008026002230015752015930038065000150197365300130198865300160200165300140201770000210203170000190205270000190207170000190209070000180210970000220212770000180214970000200216710161582016-10-10       2008    bl uuuu     u00u1 u    #d1 aCARVALHO, C. A.  aAntioxidant activity of jacaranda decurrens Cham.h[electronic resource]  aIn: Planta Médica, Dordrecht, v.74, n.3, p.337, 2008. Abstracts of the 7 th Annual Oxford International Conference on the Science of Botanicals & American Society of Pharmacognosy 4th Interim Meeting, Oxford, MSc2008  aMany diseases and related degenerative processes including heart, câncer and Parkinson diseases are associated with rcactive oxygen species (ROS). In an effort Io preveni diseases, search for com-pounds with antioxidant activity hás been a major interestof dif-ferent research groups in natural products research. The objective of this research was to investigatethe antioxidant activity of EtOH leaf extract ofjacarando decurrrens and its fractions using the 2,2-diphenyl-2-picrylhydrazyl hydrate (DPPH) assay [lJ, that uses s pé ciro me t ric method to determine radical scavenging activity, Rutinattheconcçntrationof l.Omg-L was used as the standard. Our results ha vê shown lhat crude extract and fractions had anti-oxidant activities mainly if tested at concentrations of 5.0 to 10.0mg-L. such activities, however. were lesser or equal to the standard (Table 1). The triterpenes, ursolic and oleanohc acids, were detected in the crude extract, Jd-1 and Jd-2, Possibly, these triterpenes are the active constituents responsible for the antioxi-dant activity |2j. At lower concentrations (0,6mg-L than the standard. Jd-3 fraction was the most active. The presenceof flavo-noids and glycosilated compounds were detected in jcl-3 fraction (2], This is the first attempt to demonstrate antioxidant activities found i n Já cara n (ia decurrens leaf extracts. Acknowledgements. Re-search funded by FAPESP. The State of São Paulo Research Founda-tion. Brazil, Referentes: 11) Koleva I. et ai. (2002). Phytochem Anal. 13: 8-17, (2! Oh CJ, et ai. (2007)- Free Radie Rés. 41(6): 638-44.  aJacarandá  aActivity  aAntioxidant  aDecurrens1 aLOURENÇO, M. V.1 aBERTONI, B. W.1 aFRANÇA, S. C.1 aPEREIRA, P. S.1 aFACHIN, A. L.1 aPEREIRA, A. M. S.1 aMORAES, R. M.1 aCERDEIRA, A. L.