02351naa a2200277 a 450000100080000000500110000800800410001902400590006010000280011924501950014726000090034252014230035165000160177465300120179065300270180270000220182970000260185170000200187770000230189770000200192070000180194070000170195870000200197570000210199577300570201621827672025-12-16 2025 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1016/j.smallrumres.2025.1076282DOI1 aGUIMARÃES, L. J. A. F. aHomeopathic intervention enhances osteoarthritis management and productivity in dairy goats with Small Ruminant LentivirusesbA triple-blind, placebo-controlled study.h[electronic resource] c2025 aAbstract - Small ruminant lentiviruses (SRLV) impact productivity, health, and welfare. With no effective treatments available, homeopathy offers a safe, low-cost, residue-free alternative. This study evaluated two distinct homeopathic protocols, a homeopathic nosode (Gnosode) and a homeopathic complex of plant/mineral origin (Ghomeopathic), using a triple-blind, placebo-controlled design in SRLV-infected goats. Forty-two Saanen goats with SRLV-confirmed chronic osteoarthritis and weight loss were randomly assigned to three groups: SRLV nosode (Gnosode; n = 14), homeopathic complex (Ghomeopathic; n = 14), or placebo (Gplacebo; n = 14). Treatments were administered orally (1 mL/day) for 90 days. Monthly assessments included clinical exams, joint ultrasound, and milk production records. Both homeopathic groups showed significant improvements (p < 0.05) in body condition score, weight, articular index and joint width compared to placebo. Ultrasound revealed lower carpal joint lesion measures in treated groups, including reduced distance from the joint capsule to the subchondral space, area, and perimeter of lesions (p < 0.05). Homeopathic treatments improved clinical and ultrasound outcomes, as well as productive parameters, in SRLV-infected goats. These results suggest homeopathy as a promising tool for managing chronic osteoarthritis and weight loss associated with SRLV. aDairy goats aGnosode aHomeopathic treatments1 aSANTOS, L. S. dos1 aOLIVEIRA, T. P. B. de1 aPINHEIRO, R. R.1 aMELLO, M. L. V. de1 aPAIVA, J. P. de1 aHOLANDINO, C.1 aSANAVRIA, A.1 aCUNHA, N. C. da1 aBALARO, M. F. A. tSmall Ruminant Researchgv. 253, e107628, Dec. 2025.