03144naa a2200289 a 450000100080000000500110000800800410001902400540006010000210011424501770013526000090031252021750032165300230249665300260251965300260254565300340257170000240260570000220262970000260265170000260267770000200270370000210272370000190274470000190276370000190278277300530280121773662025-07-17       2025    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.dental.2025.06.0022DOI1 aSILVESTRE, F. A.  aEvaluation of the physicochemical and adhesive properties of an etch-and-rinse adhesive system incorporated with magnesium whitlockite nanoparticles.h[electronic resource]  c2025  aObjective: To synthesize and characterize magnesium whitlockite nanoparticles (nMg-WH) to evaluate the physicochemical and adhesive properties of a conventional adhesive incorporating different concentrations of nMg-WH. Method: nMg-WH were synthesized using a hydrothermal method and characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and transmission electron microscopy (TEM). Six groups of adhesive systems were prepared with different concentrations of nMg-WH (wt%: 0 % [Control], 0.1 %, 0.2 %, 0.5 %, 1 %, and 2 %) to evaluate the degree of conversion (DC, %), viscosity (cP), water sorption (WS, μg/mm³), and solubility (SL, μg/mm³). Forty-eight molars (n = 8) were sectioned and randomized between groups and evaluated for contact angle (in degrees) and microshear bond strength (μSBS), before and after thermocycling (TC) involving 10,000 cycles with a 30-s immersion time at temperatures of 5 ◦C and 55 ◦C. Statistical analysis was performed using one-way ANOVA (DC, cP, WS and SL) or mixed ANOVA (μSBS), followed by Tukey’s test for multiple comparisons (α = 0.05). Results: Regarding the physicochemical properties, the 0.2 % (51.3 ± 0.3), 0.5 % (49.0 ± 1.4), and 1 % (49.2 ± 1.9) nMg-WH groups showed significantly higher DC compared to the control (41.0 ± 0.2). The 0.2 % group presented the lowest contact angle (16.24 ± 7.79), indicating enhanced wettability. Viscosity increased proportionally with concentration, although 0.1 % (28.91 ± 0.75) remained comparable (p &gt 0.05) to the control (31.00 ± 1.08). WS and SL were not significantly affected at higher concentrations (0.5 %, 1 %, and 2 %). Before TC, the 0.1 % (32.1 ± 4.0) and 0.2 % (30.9 ± 2.1) nMg-WH groups demonstrated statistically higher (p &lt 0.05) μSBS values than the control (18.0 ± 5.2). After TC, concentrations of 0.2–2 % exhibited higher μSBS compared to the control, with the 0.5 % nMg-WH group showing the highest value (31.8 ± 1.0). Significance: nMg-WH improved the physicochemical properties of the adhesive system and increased adhesion to dentin, particularly at concentrations ranging from 0.2 % to 1 %  aChemical phenomena  aDentin-bonding agents  aMagnesium whitlockite  aMultifunctional nanoparticles1 aANDRADE NETO, D. M.1 aARAÚJO, A. C. R.1 aFERREIRA, M. A. DE A.1 aOLIVEIRA, D. L. V. DE1 aMARCIANO, S. J.1 aMATTOS, A. L. A.1 aMOREIRA, M. M.1 aFEITOSA, V. P.1 aPEIXOTO, R. F.  tDental Materials, V. 41, N. 8, P. 938-946, 2025.