02424naa a2200265 a 450000100080000000500110000800800410001902400550006010000250011524501690014026000090030952015280031865000160184665000150186265000180187765000200189565000210191570000240193670000200196070000230198070000210200370000230202470000200204777300910206721762382025-06-02       2025    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1080/15287394.2024.24349522DOI1 aROSA, S. D. V. F. da  aAllelopathic activity of coffee extractsbimplications for germination and initial growth in select weeds and polyploidy in Lactuca sativa L.h[electronic resource]  c2025  aCoffee beans contain compounds with allelopathic activity, such that some beans that do not meetquality standards might rather be used to obtain a natural herbicide which consequently might beemployed to control undesired plants and avoid economic losses. Thus, the objectives of this studywere: (1) to investigate the allelopathic effect of different concentrations of green (GC) and roasted(RC) coffee extracts on the inhibition of germination and initial growth of Lactuca sativa L. Bidenspilosa L. and Cyperus rotundus L. and (2) determine the induction of changes in the cell cycle of L. sativa L. and (3) quantify some compounds in the GC and RC extracts with possible allelopathic effects. Seeds and tubers were sown on germination paper, moistened with water or different concentrations of extracts, stored in transparent plastic boxes, and maintained in a germination chamber. Caffeine was found at higher concentrations of 79.768 and 15.532 g/L in GC and RC extracts, respectively. In general, RC extract for L. sativa L. and GC for B. pilosa L. diminished germination parameters. For C. rotundus L. GC extract decreased growth regardless of the concentration. An increased frequency of cell cycle alterations was observed in the root cells of L. sativa L. This study is the first to report that the studied extracts possess allelopathic potential, as they areeffective in reducing germination and/or initial growth of weed species and L. sativa L. as well asinducing alterations in the cell cycle of L. sativa L.  aGermination  aHerbicides  aBidens Pilosa  aCoffea Arábica  aCyperus Rotundus1 aVILELA, A. L. de O.1 aALVES, M. V. P.1 aCARDOSO, M. das G.1 aVIEIRA, L. F. A.1 aFERREIRA, A. M. O.1 aSILVA, L. M. da  tJournal of Toxicology and Environmental Health, Part Agv. 88, n. 6, p. 250-262, 2025.