02248naa a2200277 a 450000100080000000500110000800800410001902400430006010000210010324501520012426000090027652013920028565000130167765000230169065000160171365000110172965300150174065300310175565300250178670000190181170000190183070000240184970000200187370000200189377300570191321750102025-04-22       2025    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1111/jmp.700182DOI1 aFELIZARDO, G. F.  aEvaluation of the hematological and biochemical profile of Leontopithecus chrysomelas (Kuhl, 1820) under ex-situ conditions.h[electronic resource]  c2025  aLeontopithecus chrysomelas is a neotropical primate in danger of extinction and its ex-situ maintenance is one of the species' conservation and preservation strategies. Knowledge of biological standards of normality, such as hematological and biochemical analytes, provides valuable information on the animals' state of health and aids in the diagnosis of diseases. Methods: Blood samples from 65 individuals of the species L. chrysomelas were collected and analyzed for complete blood count analytes and biochemical analytes. Each variable was statistically analyzed according to the ASVCP guidelines and compared between the sexes. Results: This study provides hematological and biochemical reference values for L. chrysomelas under humane care. Statistical differences were observed between the sexes in hematological and biochemical analytes. Differences were observed in hemoglobinometry and mean corpuscular volume (MCV), in which males showed higher values (p&lt0.05). Considering the biochemical analytes, the males of L. chrysomelas showed higher alkaline phosphatase values compared to the females (p&lt0.05). Conclusions: Our study provides the first reports of hematological and biochemical reference values for L. chrysomelas ex-situ. The normal ranges described can be used for the management, diagnosis, monitoring, and disease prevention of animals in similar conditions.  aPrimates  aBioquímica Animal  aHematologia  aMacaco  aMico-leão  aMico-leão-de-cara-dourada  aValor de referência1 aMOREIRA, S. B.1 aPISSINATTI, A.1 aALCANTARA, A. de O.1 aSOUZA, G. N. de1 aSOUZA, A. M. de  tJournal of Medical Primatologygv. 54, e70018, 2025.