02006naa a2200277 a 450000100080000000500110000800800410001902400530006010000200011324501110013326000090024450000350025352011600028865000130144865300280146165300310148965300250152070000180154570000150156370000190157870000280159770000150162570000190164070000200165977300490167921741312025-03-24       2025    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.jprot.2025.1053872DOI1 aSOUSA, L. J. de  aNew potential susceptibility factors contributing to tomato bacterial spot disease.h[electronic resource]  c2025  aNa publicação: Angela Mehta.  aThe label-free shotgun proteomics analysis carried out in this study aimed to understand the molecular mechanisms that contribute towards tomato susceptibility to Xanthomonas euvesicatoria pv. perforans (Xep). To achieve this, comparative proteomics was performed on susceptible inoculated plants with the bacterium and the control group (saline solution) at 24 and 48 h after inoculation (hai). The results revealed that most of the identified proteins showed increased abundance in the infected group and were classified into different gene ontology groups. Eight of these proteins were related to susceptibility in other pathosystems, suggesting their potential involvement in the development of bacterial spot in tomato. Some of these proteins are involved in the negative regulation of salicylic acid, PR proteins and reactive oxygen species (ROS), as well as contributing to the acquisition of sugars by the pathogen. The results obtained in this study provided us with valuable information for understanding the molecular mechanisms that lead to tomato susceptibility to Xep and will help in developing tomato cultivars resistant to bacterial spot.  aProteins  aDifferential expression  aPlant-pathogen interaction  aRecessive resistance1 aSANTOS, I. R.1 aLUZ, I. S.1 aRIBEIRO, D. G.1 aOLIVEIRA-NETO, O. B. de1 aFONTES, W.1 aBLUM, L. E. B.1 aREIS, A. M. dos  tJournal of Proteomicsgv. 314, 105387, 2025.