02910naa a2200469 a 450000100080000000500110000800800410001902400540006010000180011424501730013226000090030552013470031465000190166165000230168065000250170365000200172865300240174865300420177265300280181465300320184265300540187465300120192865300100194065300080195065300420195865300350200065301200203570000160215570000180217170000150218970000180220470000200222270000180224270000170226070000180227770000170229570000150231270000180232770000170234570000220236277300560238421661522024-09-24       2024    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.chroma.2024.4652082DOI1 aCUCINOTTA, L.  aGas chromatographic techniques and spectroscopic approaches for a deep characterization of Piper gaudichaudianum Kunth essential oil from Brazil.h[electronic resource]  c2024  aPiper gaudichaudianum Kunth essential oil (EO) is a natural source of bioactive components, having multiple therapeutic applications. Its chemical composition is highly variable, and strictly depends on abiotic factors, resulting in various biological activities. The present study details the utilization of multiple gas chromatographic techniques alongside nuclear magnetic resonance (NMR) spectroscopy to characterize the essential oil of Piper gaudichaudianum Kunth from Brazil. Seventy-six components were identified using GC–MS analysis, while enantio‐selective multidimensional gas chromatography elucidated the enantiomeric distribution of eight chiral components, for the first time in the literature. Following GC–MS analysis, an unidentified component, constituting approximately 27 % of the total oil, prompted an isolation step through preparative gas chromatography. Through the combined use of nuclear magnetic resonance, GC-Fourier transform infrared spectroscopy (FTIR), and mass spectrometry (MS), the unknown molecule was structurally identified as 4-[(3E)‐dec-3-en-1-yl]phenol. Remarkably, it was identified as a known molecule, gibbilimbol B, and not previously listed in any MS database. Subsequently, the spectrum was included in a commercial library, specifically the FFNSC 4.0 MS database, for the first time.  aEssential oils  aGas chromatography  aCromatografia Gasosa  aÓleo Essencial  aComponentes quirais  aCromatografia gasosa multidimensional  aEnantiomeric separation  aEspectometria de massa (MS)  aEspectroscopia de ressonância magnética nuclear  aGC-FTIR  aGC-MS  aNMR  aPiper gaudichaudianum Kunth do Brasil  aPreparative gas chromatography  aUso combinado de ressonância magnética nuclear espectroscopia de infravermelho com transformada GC-Fourier (FTIR)1 aROTONDO, A.1 aCOPPOLINO, C.1 aIRRERA, E.1 aDUARTE, L. A.1 aCIPRIANO, R. R.1 aAMARAL, W. do1 aLOUREIRO, W.1 aDESCHAMPS, C.1 aBIZZO, H. R.1 aDONATO, P.1 aSCIARRONE, D.1 aMONDELLO, L.1 aSALERNO, T. M. G.  tJournal of Chromatography Agv. 1732, 465208, 2024.