02092naa a2200277 a 450000100080000000500110000800800410001902400550006010000120011524501720012726000090029952012450030865000190155365000090157265300200158165300180160165300190161965300260163865300160166465300210168070000110170170000110171270000190172370000140174277300580175621652942024-07-02       2024    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.jhazmat.2024.1350112DOI1 aYAN, Q.  aComparative transcriptome analyses reveal regulatory network and hub genes of aluminum response in roots of elephant grass (Cenchrus purpureus).h[electronic resource]  c2024  aAluminum (Al) toxicity severely restricts the growth and productivity of elephant grass in acidic soils around the world. However, the molecular mechanisms of Al response have not been investigated in elephant grass. In this study, we conducted phenotype, physiology, and transcriptome analysis of elephant grass roots in response to Al stress. Phenotypic analysis revealed that a low concentration of Al stress improved root growth while higher Al concentrations inhibit root growth. Al stress significantly increased the citrate (CA) content in roots, while the expression levels of genes related to citrate synthesis were substantially changed. The multidrug and toxic compound extrusion (MATE) family were identified as hub genes in the co-expression network of Al response in elephant grass roots. Phylogenetic analysis showed that hub genes CpMATE93 and CpMATE158 belonged to the same clade as other MATE genes reported to be involved in citrate transport. Additionally, overexpression of CpMATE93 conferred Al resistance in yeast cells. These results provide a theoretical basis for further studies of molecular mechanisms in the elephant grass response to Al stress and could help breeders develop elite cultivars with Al tolerance.  aCapim Elefante  aGene  aAluminum stress  aCo-expression  aElephant grass  aEstresse de alumínio  aGene family  aTranscriptômico1 aLU, L.1 aYI, X.1 aPEREIRA, J. F.1 aZHANG, J.  tJournal of Hazardous Materialsgv. 476, 135011, 2024.