01965naa a2200289 a 450000100080000000500110000800800410001902400390006010000300009924501730012926000090030252010280031165000150133965000150135465300170136965300180138665300470140470000230145170000300147470000200150470000190152470000200154370000200156370000190158370000220160277300510162421648012024-10-23       2024    bl uuuu     u00u1 u    #d7 a10.1080/14786419.2024.23124182DOI1 aRIBEIRO JÚNIOR, K. A. L.  aLarvicidal activity of diterpenes from Xylopia langsdorfiana St. Hilaire & Tulasne (Annonaceae) against Aedes aegypti linn. (dipterabculicidae).h[electronic resource]  c2024  aMosquitoes of the Aedes genus are responsible for transmitting many vector-borne viral diseases worldwide. Hundreds of thousands of people die annually from vector-borne diseases, including West Nile fever, dengue, tick-borne diseases, yellow fever, chikungunya, Rift Valley fever, and Zika. Billions of people are at the risk of infection on all continents, which is a cause of international concern. Therefore, new vector-control methods are essential for mitigating these illnesses. The bioactive hydrocarbons isolated from Xylopia langsdorfiana St. Hilaire & Tulasne are trachylobanes, a rare class of diterpenes found in the n-hexane fraction of the stem and leaf ethanolic extracts. These were tested against Ae. aegypti fourth-instar larvae over 48 h of exposure, with LC50 values ranging from 19.84 to 72.9 µg/mL, comparable to that of the positive control. The findings highlight the potential of Xylopia langsdorfiana St. Hilaire & Tulasne metabolites for controlling the main vectors of arthropod-borne viruses.  aLarvicides  aAnnonaceae  aAedes larvae  aTrachylobanes  aXylopia langsdorfiana St Hilaire & tulasne1 aSILVA, S. A. S. DA1 aARAÚJO JÚNIOR, J. X. DE1 aCOSTA, J. G. da1 aGOULART, H. F.1 aBERNARDO, V. B.1 aSILVA, M. S. DA1 aTAVARES, J. F.1 aSANTANA, A. E. G.  tNatural Product Research, p. 1–7, feb. 2024.