01372naa a2200361 a 450000100080000000500110000800800410001902400520006010000170011224501510012926000090028052002570028965000180054665000160056465000100058065300310059065300150062165300210063665300260065765300220068370000300070570000170073570000170075270000230076970000230079270000230081570000260083870000240086470000200088870000210090870000220092977300590095121515852023-09-06 2023 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1007/s00203-023-03414-12DOI1 aSOUSA, T. F. aDiscovery of dual PKS involved in sclerotiorin biosynthesis in Penicillium meliponae using genome mining and gene knockout.h[electronic resource] c2023 aIn this work, the gene knockout of two PKS together with mass spectrometry data provide evidence of a BGC for the production of sclerotiorin and sclerotiorin-like metabolites; on the other hand, the biosynthesis pathway for these molecules is proposed. aGenome mining aPolyketides aFungo aBiosynthetic gene clusters aFungal BGC aNatural products aPenicillium meliponae aProdutos naturais1 aARAÚJO JÚNIOR, M. B. de1 aPERES, E. G.1 aSOUZA, M. P.1 aSILVA, F. M. A. da1 aMEDEIROS, L. S. de1 aSOUZA, A. D. L. de1 aSOUZA, A. Q. L. de S.1 aYAMAGISHI, M. E. B.1 aSILVA, G. F. da1 aKOOLEN, H. H. F.1 aQUEIROZ, M. V. de tArchives of Microbiologygv. 205, n. 2, 75, Feb. 2023.