01997naa a2200253 a 450000100080000000500110000800800410001910000190006024500760007926000090015552013510016465000140151565000090152965000080153865300090154665300130155565300150156870000170158370000200160070000190162070000180163970000190165777300670167621490502023-07-15       2023    bl uuuu     u00u1 u    #d1 aHAJIBOLAND, R.  aAluminum toxicity in plantsbpresent and future.h[electronic resource]  c2023  aToxic aluminum ions (Al3+) found in acidic soils are absorbed by plants and interact with multiple sites during plant development, affecting especially the root growth. The mechanisms by which plants cope with Al3+ stress are variable, and Al3+ can be excluded or accumulated internally. The molecular and physiological mechanisms associated with Al3+ response have been substantially studied. Thus, reviewing the findings about these mechanisms is important to portrait the state-of-theart of Al3+ response in plants, highlight key results, identify research gaps, and ask new questions. In this paper, we discuss the current knowledge about DNA damage response induced by Al3+, as well as membrane transporters that avoid Al3+ toxicity in the apoplast, Al3+ exclusion mechanisms, how Al3+ influences plant nutrition, signaling pathways evoked by Al3+ affecting gene expression, changes in plant growth regulators concentrations caused by Al3+ toxicity, and beneficial effects of microorganisms on plants exposed to Al3+ stress. The future research on these topics is also discussed. The current and future knowledge of how plants cope with Al3+ stress is important to comprehend the inter- and intraspecies variability of Al3+ response and to pave the way for new molecular breeding targets that can improve plant performance under Al3+ stress.  aAlumínio  aDano  aDNA  aAl3+  aEstresse  aToxicidade1 aPANDA, C. K.1 aLASTOCHKINA, O.1 aGAVASSI, M. A.1 aHABERMANN, G.1 aPEREIRA, J. F.  tJournal of Plant Growth Regulationgv. 42, p. 3967-3999, 2023.