03714naa a2200373 a 450000100080000000500110000800800410001902200140006002400550007410000170012924501040014626000090025052025640025965000190282365000300284265000220287265000270289465000250292165000240294665000220297065000200299265000350301265000150304765000160306265300190307865300320309765300250312965300290315470000180318370000160320170000230321770000190324077300810325921461332022-09-05       2022    bl uuuu     u00u1 u    #d  a2168-04857 ahttps://doi.org/10.1021/acssuschemeng.2c040212DOI1 aELIAS, A. M.  aEconomic aspects on the production of biofertilizers as granular composites.h[electronic resource]  c2022  aAbstract: Biofertilizers that associate biological P-solubilization and plant disease control are sustainable alternatives to mitigate the impact of conventional phosphate fertilizers and agrochemicals in agriculture. However, the economic aspect is critical given that these bio-based products innovate in well-consolidated markets. Thus, we proposed and evaluated, from a techno-economic analysis (TEA) perspective, three different processes for biofertilizer production. The cases differ in terms of downstream processing and the use of single (SM) or double microorganisms (DM), following the concept of a granule bioreactor. In SM cases, Trichoderma asperelloides fungi act as a biocontrol agent, while in the DM case, Aspergillus niger fungi are added to promote P-solubilization. The lowest minimum biofertilizer selling price (MBSP) was US$1.06/kg, attributed to the cases with fewer downstream steps. Moreover, the global sensitivity and uncertainty analyses indicated that the substrate cost and the final product composition significantly impact the MBSP, which fluctuates from US$0.87 to 1.29/kg. These values demonstrate the biofertilizers? competitiveness since, in addition to promoting soil fertilization, they can help control plant pathogens in a sustainable way. AB  - Biofertilizers that associate biological P-solubilization and plant disease control are sustainable alternatives to mitigate the impact of conventional phosphate fertilizers and agrochemicals in agriculture. However, the economic aspect is critical given that these bio-based products innovate in well-consolidated markets. Thus, we proposed and evaluated, from a techno-economic analysis (TEA) perspective, three different processes for biofertilizer production. The cases differ in terms of downstream processing and the use of single (SM) or double microorganisms (DM), following the concept of a granule bioreactor. In SM cases, Trichoderma asperelloides fungi act as a biocontrol agent, while in the DM case, Aspergillus niger fungi are added to promote P-solubilization. The lowest minimum biofertilizer selling price (MBSP) was US$1.06/kg, attributed to the cases with fewer downstream steps. Moreover, the global sensitivity and uncertainty analyses indicated that the substrate cost and the final product composition significantly impact the MBSP, which fluctuates from US$0.87 to 1.29/kg. These values demonstrate the biofertilizers? competitiveness since, in addition to promoting soil fertilization, they can help control plant pathogens in a sustainable way.  aBiofertilizers  aBiological control agents  aEconomic analysis  aTrichoderma asperellum  aUncertainty analysis  aAnálise Econômica  aAspergillus Niger  aBiofertilizante  aFungo Para Controle Biológico  aInoculante  aTrichoderma  aCo-inoculation  aGlobal sensitivity analysis  aMicrobial inoculants  aTechno-economic analysis1 aFAVARO, C. P.1 aBETTIOL, W.1 aOLIVEIRA, C. R. de1 aFARINAS, C. S.  tACS Sustainable Chemistry & Engineeringgv. 10, n. 31, p. 10426-10438, 2022.