01224naa a2200145 a 450000100080000000500110000800800410001910000200006024500990008026000090017952007900018865000100097870000180098877300720100621419852024-02-01 1980 bl uuuu u00u1 u #d1 aREYNOLDS, G. W. aSecretin and cholecystokinin activities in extracts of sheep intestine.h[electronic resource] c1980 aAbstract: Extracts of sheep intestine prepared to contain secretin were readily obtained, reacted with antibodies raised to pure natural porcine secretin, were potent stimulants of pancreatic exocrine secretion of the anaesthetised rat and failed to contract sheep gall bladder in vitro. In contrast extracts prepared to contain cholecystokinin (CCK) caused contraction of sheep gall bladder in vitro but were more difficult to obtain than those of secretin due to a contaminant green pigment. The experiments provide biological and immunological evidence for the existence of secretin in sheep intestine. The demonstration of CCK activity on sheep gall bladder by separate extracts is indicative of the presence of CCK in the sheep but this awaits confirmation by immunological means. aSheep1 aMCLEAY, L. M. tVeterinary Science Communicationsgv. 4, n. 1, p. 53-58, May, 1980.