02118naa a2200325 a 450000100080000000500110000800800410001902400360006010000240009624501420012026000090026252010880027165000240135965300270138365300290141065300300143970000230146970000220149270000230151470000230153770000230156070000200158370000190160370000170162270000230163970000220166270000190168470000230170377300660172621387932022-03-10       2021    bl uuuu     u00u1 u    #d7 a10.1007/s43450-021-00215-92DOI1 aFERNANDES, K. R. P.  aAsperelines produced by the endophytic fungus Trichoderma asperelloides from the aquatic plant Victoria amazonica.h[electronic resource]  c2021  aAsperelines, a family of linear peptides, produced by Trichoderma asperelloides, an endophytic strain from Victoria amazonica (Poepp.) J.C. Sowerby, Nymphaeaceae, are described. Fifteen asperelines with ten amino acid residues were identified by liquid chromatography coupled to mass spectrometry in a positive acquisition mode, using high-energy collisional dissociation. Eight of these asperelines are peptaibols of the model Ac-Aib-xxx-Val-Aib-xxx-Aib-xxx-xxx-Aib-Prolinol. The other seven have the rare proline-ending sequence type: Ac-Aib-xxx-Val-Aib-xxx-Aib-Aib-xxx-Aib-Proline. Nine new asperelines were identified, together with the known asperelines A, D, E, O, U, and Z11. A chemotaxonomic significance of the findings and the name ?peptaibes? to the aspereline types ending in amino acids are suggested. The aspereline-containing fraction showed a marginal activity against Streptococcus mutans and Staphylococcus aureus. This fraction also presented high activity against the pathogenic bacteria Listeria monocytogenes, as well as a low mortality against VERO-type cells.  aVictoria Amazônica  aAmazonian bioresources  aAquatic endophytic fungi  aTrichoderma asperelloides1 aSOUZA, A. Q. L. de1 aSANTOS, L. A. dos1 aNOGUEIRA, F. C. S.1 aEVARISTO, J. A. M.1 aCARNEIRO, G. R. A.1 aSILVA, G. F. da1 aCRUZ, J. C. da1 aSOUSA, T. F.1 aSILVA, S. R. S. da1 aBASTOS, I. dos S.1 aORLANDI, P. P.1 aSOUZA, A. D. L. de  tRevista Brasileira de Farmacognosiagv. 31, p. 667-675, 2021.