01840naa a2200409 a 450000100080000000500110000800800410001902400410006010000250010124501960012626000090032250000820033152005140041365000270092765000230095465000270097765000200100465000180102465000240104265000100106665000110107665300300108765300240111765300090114170000180115070000200116870000200118870000170120870000170122570000240124270000230126670000190128970000200130870000200132870000200134877300620136821374942021-12-10       2021    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1002/ps.64302DOI1 aMOREIRA-PINTO, C. E.  aIncreasing Anthonomus grandis susceptibility to Metarhizium anisopliae through RNAi-induced AgraRelish knockdownba perspective to combine biocontrol and biotechnology.h[electronic resource]  c2021  aNa publicação: Leonardo L P Macedo; Maria C M Silva; Maria F Grossi-de-Sa.,  aThe hemolymph and insect gut together have an essential role in the immune defense against microorganisms, including the production of antimicrobial peptides (AMP). AMPs are mainly induced by two specific signaling pathways, Toll and immune deficiency (IMD). Here, we characterize the expression profile of four genes from both pathways and describe the importance of AgraRelish in the immune defense of Anthonomus grandis against the entomopathogenic fungus Metarhizium anisopliae by RNA interference (RNAi).  aAntimicrobial peptides  aBiological control  aEntomopathogenic fungi  aInsect immunity  aBiotecnologia  aControle Biológico  aFungo  aInseto  aFungos entomopatogênicos  aImunidade a insetos  aRNAi1 aCOELHO, R. R.1 aLEITE, A. G. B.1 aSILVEIRA, D. A.1 aSOUZA, D. A.1 aLOPES, R. B.1 aMACEDO, L. L. P. de1 aSILVA, M. C. M. da1 aRIBEIRO, T. P.1 aMORGANTE, C. V.1 aANTONINO, J. D.1 aSA, M. F. G. de  tPest Management Sciencegv. 77, n. 9, p. 4054-4063, 2021.