02381naa a2200433 a 450000100080000000500110000800800410001902400560006010000230011624501660013926000090030530000270031452010820034165000260142365000240144965000220147365000160149565000170151165000140152865000120154265000100155465000130156465000140157765000230159165300230161465300230163765300260166065300280168670000170171470000230173170000190175470000160177370000280178970000160181770000230183370000200185670000230187677300480189921374492021-12-09       2022    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.foodchem.2021.1317402DOI1 aSILVA, C. de O. G.  aOutdoor versus indoor cultivationbEffects on the metabolite profile of Agaricus subrufescens strains analyzed by untargeted metabolomics.h[electronic resource]  c2022  a10 p.cPDF: il. color.  aAbstract: Agaricus subrufescens has emerged as an important culinary-medicinal mushroom over the last decades. Efforts have been dedicated to upgrade the A. subrufescens productive process via strain selection and cultivation scaling-up. However, little is known on the influence of those variables on the metabolite profiles and nutraceutical properties of this mushroom. In this work, the effects of outdoor versus indoor cultivation on the metabolite profiles of five commercial strains of A. subrufescens were investigated by untargeted metabolomics. UHPLC-MS coupled to multivariate data analysis revealed that the concentration of several metabolites with reported health-related properties as well as related to taste and browning varied significantly between strains and were affected by the cultivation system in a strain-dependent manner. Data suggest that increasing the production scale by means of indoor cultivation may decrease the nutraceutical quality of some A. subrufescens strains while also affecting taste and browning susceptibility to different extents.  aAgaricus subrufescens  aBioactive compounds  aMass spectrometry  aMetabolites  aMetabolomics  aMushrooms  aStrains  aTaste  aCogumelo  aQualidade  aSistema de Cultivo  aCultivation method  aMedicinal mushroom  aNutraceutical quality  aUntargeted metabolomics1 aCUNHA, R. B.1 aCONCEIÇÃO, A. A.1 aALMEIDA, E. G.1 aZIED, D. C.1 aVIEIRA JUNIOR, W. G. V.1 aDIAS, E. S.1 aISIKHUEMHEN, O. S.1 aABDELNUR, P. V.1 aSIQUEIRA, F. G. de  tFood Chemistrygv. 374, 131740, April 2022.