02505naa a2200361 a 450000100080000000500110000800800410001902400480006010000200010824501460012826000090027452014250028365000210170865000160172965000180174565000200176365000250178365000210180865000230182965000240185265300220187665300100189865300220190865300220193065300210195270000170197370000170199070000200200770000170202770000150204470000200205977300640207921365552021-11-25       2021    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.37496/rbz50202002292DOI1 aSILVA, M. C. da  aInnate immunity in chicken lines developed by Embrapa Suínos e Avesbantimicrobial activity of macrophages and serum.h[electronic resource]  c2021  aAbstract: The objective of this study was to compare the antimicrobial activity of macrophages and serum in laying hen (MM, CC, and CCc) and broiler chicken lineages (TT and LL). Macrophages were evaluated for phagocytic and antimicrobial activity. Microbicidal serum activity was evaluated by the resistance test for serum and the agar test. The results showed that phagocytic activity was higher in males of the MM strain, with 13% of macrophages presenting phagocytosis, while the other lineages studied, and even female MM, presented a rate of 6% of phagocytic cells. However, antimicrobial activity in macrophages from males of CCc lineage and females of TT lineage were higher, eliminating more than 30% of the Salmonella enterica inoculum, while in the other strains, the results were similar, with inoculum reduction below 30%. In the serum resistance assay, female laying lines presented higher antibacterial activity than female broiler lines. In the trials to evaluate the microbicide activity of the serum, females of both broiler and laying lineages presented higher performance when compared with males of the same lineage. Females of laying hen lines (MM and CC) present a greater antibacterium activity than males. These results can contribute to a better understanding of the immune response in broiler chicken and laying hen lineages, to aid development of lineages of birds more resistant to pathogens  aBroiler chickens  aLaying hens  aAve Domestica  aFrango de Corte  aGalinha Para Postura  aGenética Animal  aPoedeira Comercial  aSeleção Genética  aComplement system  aFowls  aGenetic selection  aImunidade natural  aNatural immunity1 aCOSTA, I. C.1 aNAKAZATO, G.1 aPINHEIRO, J. W.1 aLEDUR, M. C.1 aLOYOLA, W.1 aVENANCIO, E. J.  tRevista Brasileira de Zootecniagv. 50, n. e20200229, 2021.