02163naa a2200289 a 450000100080000000500110000800800410001902200140006002400520007410000200012624501060014626000090025252012630026165000150152465000160153965000450155565000100160065000290161065000140163965000100165365300440166365300320170770000150173970000150175470000210176977300830179021349812022-03-15 2021 bl uuuu u00u1 u #d a2001-03707 ahttps://doi.org/10.1016/j.csbj.2021.01.0452DOI1 aKAVAMURA, V. N. aDefining the wheat microbiomebtowards microbiome-facilitated crop production.h[electronic resource] c2021 aAbstract: Wheat is one of the world's most important crops, but its production relies heavily on agrochemical inputs which can be harmful to the environment when used excessively. It is well known that a multitude of microbes interact with eukaryotic organisms, including plants, and the sum of microbes and their functions associated with a given host is termed the microbiome. Plant-microbe interactions can be beneficial, neutral or harmful to the host plant. Over the last decade, with the development of next generation DNA sequencing technology, our understanding of the plant microbiome structure has dramatically increased. Considering that defining the wheat microbiome is key to leverage crop production in a sustainable way, here we describe how different factors drive microbiome assembly in wheat, including crop management, edaphic-environmental conditions and host selection. In addition, we highlight the benefits to take a multidisciplinary approach to define and explore the wheat core microbiome to generate solutions based on microbial (synthetic) communities or single inoculants. Advances in plant microbiome research will facilitate the development of microbial strategies to guarantee a sustainable intensification of crop production. aMicrobiome aRhizosphere aSustainable agricultural intensification aWheat aAgricultura Sustentável aRizosfera aTrigo aIntensificação agrícola sustentável aSustainable intensification1 aMENDES, R.1 aBARGAZ, A.1 aMAUCHLINE, T. H. tComputational and Structural Biotechnology Journalgv. 19, p. 1200-1213, 2021.