02095naa a2200313 a 450000100080000000500110000800800410001902200140006002400530007410000210012724501680014826000090031652010720032565000230139765000170142065000120143765000270144965000240147665000180150065000220151865000350154065000270157565300320160270000140163470000220164870000200167070000260169077300650171621304472023-02-07 2021 bl uuuu u00u1 u #d a2589-014X7 ahttps://doi.org/10.1016/j.biteb.2020.1006192DOI1 aSANTOS, P. de S. aNutritional impact of low-cost substrates on biphasic fermentation for conidia production of the fungal biopesticide Metarhizium anisopliae.h[electronic resource] c2021 aAbstract: Agro-industrial wastes (by-products) were used in a biphasic fermentation system for the optimal production of Metarhizium anisopliae conidia. Submerged fermentation carried out with 45 g L?1 glucose and 36 g L?1 yeast extract rendered the highest blastospores yield within four days. Blastospores were used as the inoculum source in solid-state fermentation alternatively to conidia suspension. The solid substrates included rice, bran, and inert supports for growth and sporulation. Pre-cooked rice inoculated with blastospores showed higher yield and faster conidia production compared to inoculation with conidia. The optimal conidia production was obtained after seven days when inoculated with blastospore-based pre-culture. Conidia production after fungal growth on wheat bran (1.2 × 109 conidia g?1) was twice as high as on corn bran. Sugarcane bagasse was the best supporting matrix for growth and sporulation (5.14 × 108 conidia g?1). This study highlights the feasibility of a cost-effective biphasic liquid-solid fermentation of M. anisopliae. aBiological control aBlastospores aConidia aEntomopathogenic fungi aControle Biológico aFermentação aFungo Entomógeno aFungo Para Controle Biológico aMetarhizium Anisopliae aAgro-industrial by-products1 aABATI, K.1 aMENDOZA, N. V. R.1 aMASCARIN, G. M.1 aDELALIBERA JUNIOR, I. tBioresource Technology Reportsgv. 13, article 100619, 2021.