02218nam a2200169 a 450000100080000000500110000800800410001910000210006024501420008126001460022350003310036952012820070065300200198265300140200265300240201665300080204021179512019-12-30       2019    bl uuuu  m   00u1 u    #d1 aSUNIGA, P. A. P.  aAncestralidade genética da raça Senepol por meio da análise de painés de polimorfismos de nucleotídeo único.h[electronic resource]  aDissertação (Mestrado) - Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso do Sul, Campo Grande, MSc2019  aOrientadora: Andréa Alves do Egito, Pesquisadora da Embrapa Gado de Corte, matrícula: 257.064; Coorientador: Gilberto Romeiro de Oliveira Menezes - Pesquisador da Embrapa Gado de Corte, Matrícula: 351.204; Coorientador: Marcos Vinicius Gualberto Barbosa da Silva - Pesquisador da Embrapa Gado de Leite, Matrícula: 307.003.  aThis work aimed to evaluate the genetic ancestry of the Senepol breed by genomic analysis based on large-scale SNP (Single Nucleotide Polymorphism) markers to elucidate its genetic composition. Twenty Senepol bulls were genotyped, which were chosen based on their contribution to the Brazilian population, with the BovineHD BeadChip panel. Prior quality control was performed for samples, those with call rates above 0.9 remained in the analysis, and for markers, minor allele frequency (MAF) above 0.5 and call rates 0.95 were also maintained. Analyzes of ADMIXTURE and main components were performed. For the first analysis, the markers in high binding imbalance were removed. The results show that Senepol has, in greater proportion, allelic sharing with European taurines, compatible with its history. The proportion of African Taureans is small ( ̅ = 2%) and there is an average 14.4% introgression of Zebu alleles. In addition, it was possible to observe that a genetic composition similar to the locally adapted breeds of Brazil, being even closer genetically. It is concluded that the Senepol breed has predominantly European taurine ancestry and it was verified the participation of Creole cattle in its formation, probably through their use in absorbent crosses.  aAdapted taurine  aADMIXTURE  aGenetic composition  aSNP