02596naa a2200313 a 450000100080000000500110000800800410001902400590006010000200011924501180013926000090025752016730026665000160193965000310195565000180198665000180200465000140202265000130203665000240204965000140207365300160208765300240210370000260212770000200215370000170217370000170219070000170220777300580222421163582020-02-11       2020    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/j.smallrumres.2019.10.0132DOI1 aNOBRE, C. O. R.  aBenefits of vaccinating goats against Haemonchus contortus during gestation and lactation.h[electronic resource]  c2020  aAbstract: The effect of a vaccine made from Haemonchus contortus gut membrane glycoproteins was evaluated in pregnant and lactating dairy goats grazing native pasture on a semi-arid region of Ceara State, Brazil. Saanen (n =20) or Anglo Nubian (n = 20) does aged six months were assigned by body weight and fecal egg count into two equivalent groups (n = 10), vaccinated or naive (control), as reported earlier in a trial performed in 2017. The recommended course of immunisation for sheep was applied, with three priming doses 21 days apart followed by boosts every 6 weeks. All animals grazed the same bushland area and were exposed to natural worm infections supplemented, when needed, with additional artificial doses of Haemonchus larvae. Parasitologic and performance parameters were monitored throughout mating, pregnancy and lactation. These included faecal egg counts, Packed Cell Volumes (PCVs), plasma proteins, body weights, body condition scores and milk production as well as the incidence of mastitis causing agents. Vaccinates of both breeds showed significantly reduced (65.3% ± 10.7 for Anglo Nubians and 67.6% ± 8.9 for Saanen) egg counts compared to controls during pregancy and lactation. However only Anglo Nubians showed a positive response in packed cell volumes, plasma protein concentrations and Famacha© scores. The vaccine had no significant efffect on milk yield, quality and other performance parameters, although a reduction in the occurence of mastitis aetiologic agents was associated with it. Unlike anthelmintics, the Haemonchus vaccine does not have a withdrawal period and so it could be useful for dairy goats during lactation.  aDairy goats  aGastrointestinal nematodes  aGlycoproteins  aGoat diseases  aHelminths  aMastitis  aNematode infections  aPregnancy  aDrug effect  aLactation Barbervax1 aMATOS, A. F. I. M. de1 aMONTEIRO, J. P.1 aSOUZA, V. de1 aSMITH, W. D.1 aTEIXEIRA, M.  tSmall Ruminant Researchgv. 182, p. 46-51, Jan. 2020.