01455naa a2200301 a 450000100080000000500110000800800410001902400510006010000220011124500970013326000090023052005440023965000200078365300280080365300150083165300220084665300370086870000190090570000180092470000200094270000290096270000220099170000240101370000190103770000210105670000260107777300500110321114562019-10-10 2019 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1186/s13071-019-3663-92DOI1 aNICIURA, S. C. M. aExtreme-QTL mapping of monepantel resistance in Haemonchus contortus.h[electronic resource] c2019 aHaemonchus contortus, a gastrointestinal nematode parasite of sheep, is mainly controlled by anthelmintics; the occurrence of anthelmintic resistance leads to treatment failures and increases economic burden. Because molecular mechanisms involved in drug resistance can be elucidated by genomic studies, an extreme quantitative trait locus (X-QTL) mapping approach was used to identify co-segregation of the resistance phenotype with genetic markers to detect the genome-wide variants associated with monepantel resistance in H. contortus. aDrug resistance aAnthelmintic resistance aF2 mapping aGenome sequencing aSheep gastrointestinal nematodes1 aTIZIOTO, P. C.1 aMORAES, C. V.1 aCRUVINEL, G. G.1 aALBUQUERQUE, A. C. A. de1 aSANTANA, R. C. M.1 aCHAGAS, A. C. de S.1 aESTEVES, S. N.1 aBENAVIDES, M. V.1 aAMARANTE, A. F. T. do tParasites Vectorsgv.12, n.403, p.1-11, 2019.