02935naa a2200445 a 450000100080000000500110000800800410001902400270006010000240008724501460011126000090025752016180026665000240188465000180190865000190192665000170194565000100196265000200197265000190199265000170201165000110202865000100203965000240204965000200207365300190209365300250211265300290213765300260216670000180219270000290221070000240223970000210226370000180228470000240230270000240232670000200235070000220237070000230239277300740241521074992019-11-07       2019    bl uuuu     u00u1 u    #d7 a10.1111/rda.133742DOI1 aRODRIGUEZ, M. G. K.  aEarly luteal development in Santa Inês ewes superovulated with reduced doses of porcine follicle-stimulating hormone.h[electronic resource]  c2019  aAbstract: The aim was to compare the early luteal development in ewes superovulated with different doses of pFSH. Twenty-nine Santa Inês ewes received a progesterone device (CIDR®) for 8 days. Gonadotrophic treatment started on Day 6: G200 (control, n = 9, 200 mg); G133 (n = 10, 133 mg); and G100 (n = 10, 100 mg of pFSH). On Day 6, all females received eCG (300 IU). B-mode and spectral Doppler ultrasonography were performed daily during the early luteal phase (Days 11-15) to monitor the development of corpora lutea (CLs; dimensions) and ovarian arteries indices. CLs were also classified as normal or prematurely regressed (PRCL) on Day 15 by videolaparoscopy. Ewes from G100 and G133 showed gradual increase in luteal diameter during the early luteal phase (p &lt 0.001), whereas G200 animals presented increase from Day 11 to Day 13, and then decrease on Days 14 and 15 (p &lt 0.001). The G200 females showed greater percentage of PRCL (45.20%) than those of the other groups (p &lt 0.001). The normal CLs number was greater in G100 than in G133 (p = 0.04), while the PRCL number was greater in G200 than in the other groups (p = 0.03). Resistive index (RI) was greater in G200 than in G100 (p = 0.02). RI was lower in Day 12 than Day 15 (p = 0.02). Pulsatility index (PI) was greater on Days 14 and 15 (p &lt 0.01). In conclusion, the lowest dose of pFSH (100 mg) can be considered sufficient for an efficient superovulatory response in sheep, producing better CLs development dynamic in early luteal phase and ovarian blood perfusion and smaller number of PRCL than the traditional (200 mg) pFSH dose.  aAnimal reproduction  aCorpus luteum  aDoppler effect  aProgesterone  aSheep  aSmall ruminants  aSuperovulation  aCorpo Lúteo  aOvelha  aOvino  aReprodução Animal  aSuperovulação  aOvarian artery  aPremature luteolysis  aSpectral doppler indices  aSuperovulated females1 aMACIEL, G. S.1 aRAMIREZ USCATEGUI, R. A.1 aUSCATEGUI, R. A. R.1 aSANTOS, V. J. C.1 aNOCITI, R. P.1 aSILVA, P. del A. da1 aFELICIANO, M. A. R.1 aBRANDÃO, F. Z.1 aFONSECA, J. F. da1 aOLIVEIRA, M. E. F.  tReproduction in Domestic Animalsgv. 54, n. 3, p. 456-463, Mar. 2019.