01751naa a2200301 a 450000100080000000500110000800800410001910000200006024501390008026000090021952008870022865000160111565000160113165000190114765300270116665300260119365300140121965300120123370000260124570000200127170000170129170000180130870000180132670000190134470000180136370000200138177300480140121062332019-02-19 2018 bl uuuu u00u1 u #d1 aOLIVEIRA, G. B. aIntegrative analysis of microRNAs and mRNAs revealed regulation of composition and metabolism in Nelore cattle.h[electronic resource] c2018 aThe amount of intramuscular fat can influence the sensory characteristics and nutritional value of beef, thus the selection of animals with adequate fat deposition is important to the consumer. There is growing knowledge about the genes and pathways that control the biological processes involved in fat deposition in muscle. MicroRNAs (miRNAs) belong to a well-conserved class of non-coding small RNAs that modulate gene expression across a range of biological functions in animal development and physiology. The aim of this study was to identify differentially expressed (DE) miRNAs, regulatory candidate genes and co-expression networks related to intramuscular fat (IMF) deposition. To achieve this, we used mRNA and miRNA expression data from the Longissimus dorsi muscle of 30 Nelore steers with high (H) and low (L) genomic estimated breeding values (GEBV) for IMF deposition aBeef cattle aBos Indicus aGordura Animal aCo-expression networks aGordura intramuscular aMicroRNAs aRNA-Seq1 aREGITANO, L. C. de A.1 aCESAR, A. S. M.1 aREECY, J. M.1 aDEGAKI, K. Y.1 aPOLETI, M. D.1 aFELICIO, A. M.1 aKOLTES, J. E.1 aCOUTINHO, L. L. tBMC Genomicsgv. 19, n. 126, p. 2-16, 2018.