01793naa a2200301 a 450000100080000000500110000800800410001902400360006010000200009624501040011626000090022050000870022952008500031665000310116665300150119765300150121265300230122765300300125070000230128070000200130370000190132370000180134270000200136070000200138070000200140070000260142077300450144621021742019-02-05       2018    bl uuuu     u00u1 u    #d7 a10.1038/s41598-018-32146-22DOI1 aSOUZA, M. M. de  aA comprehensive manually-curated compendium of bovine transcription factors.h[electronic resource]  c2018  aArticle number: 13747. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano.  aTranscription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an improved comprehension of regulatory mechanisms that are specific to the species.  aGene expression regulation  aDNA bovine  aDNA bovino  aExpressão gênica  aGene expression in cattle1 aZERLOTINI NETO, A.1 aGEISTLINGER, L.1 aTIZIOTO, P. C.1 aTAYLOR, J. F.1 aROCHA, M. I. P.1 aDINIZ, W. J. S.1 aCOUTINHO, L. L.1 aREGITANO, L. C. de A.  tScientific Reportsgv. 8, p. 1-12, 2018.