02221naa a2200361 a 450000100080000000500110000800800410001910000160006024501490007626000090022550001510023452010440038565000110142965000110144065000200145165000210147165000160149265000120150865000110152065000190153165300210155065300300157165300220160165300140162370000190163770000200165670000190167670000230169570000170171870000140173570000180174977300920176720969182018-10-04       2018    bl uuuu     u00u1 u    #d1 aREIS, M. O.  aHypomyelinogenesis associated with transplacental poisoning by Sida carpinifolia (Malvaceae) in fetus and newborn calves.h[electronic resource]  c2018  aTítulo em inglês: Hipomielinogênese associada à intoxicação transplacentária por Sida carpinifolia (Malvaceae) em fetos e neonatos bovinos.  aSida carpinifolia is a plant responsible for poisoning several species of animals. This paper describes Hypomyelinogenesis in fetuses and neonates of cattle that consumed S. carpinifolia. Neonates manifested ataxia and muscle tremors. Two bovine newborns and four fetuses were necropsied and showed no significant gross changes. Histopathologic findings included vacuolation of pancreatic acinar cells, thyroid follicular cells, hepatocytes, cells of renal tubules and neurons of the fetus and the white matter of the telencephalic frontal lobe of the neonates and also revealed axonal spheroids in the brain of the fetuses and neonates. The lectin-histochemical evaluation shoved staining for the lectins Con-A, WGA and s-WGA. The Luxol Fast Blue staining revealed a marked decrease of myelin in the brain of all the fetuses and a moderate decrease in the neonates. Histologic and lectin-histochemic findings indicate that the consumption of S. carpinifolia by pregnant bovine females can cause hypomyelinogenesis in fetuses and neonates.  aCalves  aCattle  aPlant poisoning  aPoisonous plants  aSwainsonine  aBezerro  aBovino  aPlanta Tóxica  aAlfa-manosidosis  aLysosomal storage disease  aSida carpinifolia  aToxicoses1 aCRUZ, R. A. S.1 aBASSUINO, D. M.1 aBOABAID, F. M.1 aOLIVEIRA, L. G. S.1 aMELLO, L. S.1 aSONNE, L.1 aDRIEMEIER, D.  tPesquisa Veterinária Brasileira, Rio de Janeirogv. 38, n. 7, p. 1371-1375, julho 2018