01325naa a2200265 a 450000100080000000500110000800800410001910000170006024500850007726000090016252006360017165000220080765000110082965000120084065000100085265000170086265000140087965000170089365000110091065000140092165300170093565300210095270000160097377300700098920959202018-09-18       1980    bl uuuu     u00u1 u    #d1 aCOOKE, R. G.  aRemoval of corpora lutea in pregnant goatsbeffect of intrauterine indomethacin.  c1980  aAbstract: Removal of corpora lutea from seven goats during late pregnancy (122 to 129 days) resulted in an abrupt decline in uterine venous plasma progesterone concentrations within 10 min and abortion after a mean interval of 29.88 +/- 1.64 (SD) h. Abortion was preceded by a significant increase in uterine venous plasma PGF concentration either before or coincident with palpable cervical softening. Intrauterine, extra-fetal administration of indomethacin, as a single dose, in a further five lutectomised goats significantly prolonged the interval to abortion and delayed both cervical ripening and the increase in plasma PGF.  aAnimal physiology  aDosage  aEstrone  aGoats  aIndomethacin  aPregnancy  aProgesterone  aUterus  aEstradiol  aDrug effects  aProstaglandins F1 aKNIFTON, A.  tResearch in Veterinary Sciencegv. 29, n. 1, p. 77-84, Jul. 1980.