01033naa a2200169 a 450000100080000000500110000800800410001910000170006024500930007726000090017052005010017965000100068070000160069070000160070670000180072277301230074020884812018-03-02 2002 bl uuuu u00u1 u #d1 aHEINTGES, U. aLeptin and its effect on glucose and insulin metabolism in pregnant and lactating goats. c2002 aDecreased GIR together with lower insulin serum levels in leptin treated versus control pregnant goats indicate that insulin sensitivity was increased by leptin treatment during pregnancy. In lactating goats, leptin application led to higher glucose turnover-rates than in pregnant animals. Our results indicate that the effectiveness of exogenous leptin to alter glucose metabolism is dependent of the physiological state of the animal, i.e. that pregnant and lactating dams respond divergently. aGoats1 aHENNIES, M.1 aGERTLER, A.1 aSAUERWEIN, H. tIn: ANNUAL MEETING OF THE BRITISH SOCIETY OF ANIMAL SCIENCE, 2002, York. Proceedings... Medlothian: BSAS, 2002. p. 96.