02529naa a2200421 a 450000100080000000500110000800800410001910000190006024501560007926000090023552013060024465000310155065000230158165000210160465000200162565000150164565000130166065000220167365000200169565000230171565000240173865000220176265000210178465000120180565300200181765300190183765300220185665300210187870000210189970000200192070000150194070000210195570000180197670000230199470000210201770000230203877300460206120882072018-05-04 2018 bl uuuu u00u1 u #d1 aRIBEIRO, S. C. aAntioxidants effects and resistance against pathogens of Colossoma macropomum (Serassalmidae) fed Mentha piperita essential oil.h[electronic resource] c2018 aImmunostimulants in farmed fish diets has been considered an effective approach to health management. This study aimed to assess antioxidant effects and resistance against pathogens of Colossoma macropomum (tambaqui) fed essential oil (EO) of M. piperita at 0%, 0.5%, 1.0% and 1.5% kg−1 commercial feed during 30 days. Tambaqui were challenged with Aeromonas hydrophila and did not present clinical signs of alterations. Higher hepatic catalase activity was observed in fish fed 1.0% of M. piperita EO, compared with 1.5%. Renal superoxide dismutase and glutathione peroxidase decreased in the fish fed M. piperita EO. Hepatic and renal lipid hydroperoxide increased among fish fed diets with 1.0 and 1.5% of EO. Tambaqui fed 1.0% of M. piperita EO showed respiratory activity increase, compared with 0.5%. Monocytes and PAS-GL were abundant in fish fed higher EO concentrations. Reduction in monogenoideans abundance was observed in fish fed 0.5 and 1.0% of EO. Although anti-helminth effects were observed, M. piperita EO in tambaqui diet did not promote leukocytes and lysozyme activity increases at the concentrations assessed. It can be suggested that other concentrations should be tested in future studies, as the combined use with other products, such as immunostimulants and probiotics. aAnimal parasites and pests aChemical reactions aFood consumption aFreshwater fish aLeukocytes aToxicity aConsumo alimentar aGlóbulo branco aParasito de animal aPeixe de água doce aPlanta aromática aReação quimica aToxidez aAnimal parasite aAromatic plant aChemical reaction aWhite blood cell1 aMALHEIROS, D. F.1 aGUILOZKI, I. C.1 aMAJOLO, C.1 aCHAVES, F. C. M.1 aCHAGAS, E. C.1 aASSIS, H. C. S. de1 aTAVARES-DIAS, M.1 aYOSHIOKA, E. T. O. tAquaculturegv. 490, p. 29-34, Jan. 2018.