02217naa a2200337 a 450000100080000000500110000800800410001910000230006024501400008326000090022350001480023252010920038065000100147265000160148265000100149865000320150865000110154065000120155165000210156365000150158465000100159965300220160965300350163170000200166670000180168670000190170470000240172370000200174770000160176777300960178320817862017-12-29       2017    bl uuuu     u00u1 u    #d1 aNUNES, A. C. B. T.  aTransplacental transmission of Neospora caninum in naturally infected small ruminants from northeastern Brazil1.h[electronic resource]  c2017  aTítulo em português: Transmissão transplacentária de Neospora caninum em pequenos ruminantes infectados naturalmente do Nordeste do Brasil.  aToxoplasma gondii and Neospora caninum are causative agents of abortion in sheep and goats. Thus, the present study aimed to describe the transplacental transmission of these protozoans in small ruminants of northeastern Brazil. Seventeen fetuses (6 goats and 11 sheep) from farms with history of abortion were necropsied and samples were collected from different tissues (brain, liver, lung, kidney and heart). The samples were analyzed by PCR, histopathology (HP) and immunohistochemistry (IHC) to evaluate whether T. gondii and/ or N. caninum infection were the cause of abortion. None of the samples was positive for T. gondii according to PCR and IHC results. Some brain, liver, lung, kidney and heart samples of goat fetuses were positive for N. caninum by PCR. In the histopathology, mild mononuclear infiltration and necrosis with calcification were observed in the liver and brain of one goat fetus, respectively, that also was positive for N. caninum by PCR and IHC. The results confirmed vertical transmission of N. caninum in naturally infected goats of northeastern, Brazil.  aGoats  aNeosporosis  aSheep  atransplacental transmission  aAborto  aCaprino  aNeospora Caninum  aNeosporose  aOvino  aAbortion (animal)  aTransmissão transplacentária1 aYAMASAKI, E. M.1 aKIM, P. C. P.1 aMELO, R. P. B.1 aRIBEIRO-ANDRADE, M.1 aPORTO, W. J. N.1 aMOTA, R. A.  tPesquisa Veterinária Brasileira, Rio de Janeirogv. 37, n. 9, p. 921-925,, setembro. 2017.