01844naa a2200229 a 450000100080000000500110000800800410001902400420006010000220010224500970012426000090022152011620023065000190139265000100141165000190142165300210144065300290146170000150149070000170150570000130152277300790153520728502017-07-18       1994    bl uuuu     u00u1 u    #d7 ahttp://doi.org/10.1262/jrd.40.272DOI1 aZUCCOLILLI, G. O.  aSexual dimorphism of gonadotropin-releasing hormone (GnRH) neurons in the goat hypothalamus.  c1994  aA study was conducted to examine if gonadotropin-releasing hormone (GnRH) neurons show sex-related differences in the hypothalamus of the mature goat. The localization of GnRH neurons were made evident immunohistochemically using a monoclonal antibody against GnRH in coronal sections (40?m thick) of the hypothalamic area of male and female goats. The localization of immunoreactive GnRH (GnRH-ir) cell bodies was assessed according to the stereotaxic coordinates of the brain atlas for the Shiba goat, and was compared between the male and the female brains. The morphological characteristics and distribution pattern of GnRH-ir neurons, and the projection pattern of GnRH-ir fibers were similar between the sexes. On the other hand, the number of GnRH-ir neurons showed sexual dimorphism; the estimated total number of GnRH cell bodies in the hypothalamus of the male goat (4, 020 ± 572, Mean ± SEM) was greater (P&lt0.01) than that for the female (2, 223 ± 284). These results indicate that the goats of both sexes have a similar GnRH neurosecretory system, although the male goat has a greater population of GnRH neurons in the rostral hypothalamus.  aAnimal tissues  aGoats  aNervous system  aAnimal structure  aImmunological techniques1 aHAMADA, T.1 aICHIKAWA, M.1 aMORI, Y.  tJournal of Reproduction and Developmentgv. 40, n. 1, p. 27-32, Feb. 1994.