01870naa a2200301 a 450000100080000000500110000800800410001902400510006010000180011124501220012926000090025152009740026065000100123465000140124465000210125865000190127965000160129865000180131465300160133265300220134865300140137070000280138470000190141270000180143170000210144970000190147077300790148920685802017-04-24       2016    bl uuuu     u00u1 u    #d7 ahttp://doi.org/10.1016/j.jaap.2016.03.0052DOI1 aCOLMAN, M. D.  aEvolved gas analysis (TG-DSC-FTIR) and (Pyr-GC-MS) in the disposal of medicines (aceclofenac).h[electronic resource]  c2016  aDuring the twentieth century the growth of industrialisation, urbanisation and populations culminatedin huge areas of waste disposal worldwide. Consequently, the management of the disposal of medicines(expired or not) is important in order to minimise the possibility of environmental pollution. A sample ofaceclofenac (purity = 99.77% and m.p. = 151.63?C) was analysed by TG-DSC-FTIR in nitrogen atmosphere.The TG-DSC curves showed two main stages of decomposition, with loss of organic matter generatingcarbonaceous derivatives as final residue. The use of coupled FTIR suggested the loss of CO, CO2and/or2-chloro-propanoic acid/2-chloro-butanoic acid. The use of fast pyrolysis (Pyr) coupled with GC–MSsuggested that the main compounds that were released were 1-(2,6-dichlorophenyl)-2-indolinone and2,6-dichloro-N-(2-methylphenyl)–benzenamine. The differences in the results between the techniqueswere due to the experimental conditions used for each instrument.  aDrugs  aPyrolysis  aThermal analysis  aContaminação  aMedicamento  aMeio ambiente  aAceclofenac  aAnálise térmica  aPirólise1 aLAZZAROTTO, S. R. da S.1 aLAZZAROTTO, M.1 aHANSEL, F. A.1 aCOLMAN, T. A. D.1 aSCHNITZLER, E.  tJournal of Analytical and Applied Pyrolysisgv. 119, p. 157-161, May 2016.