02484naa a2200349 a 450000100080000000500110000800800410001910000220006024501180008226000090020052014840020965000160169365000150170965000260172465000100175065000260176065000190178665000200180565000120182565300160183765300160185365300230186965300100189270000180190270000200192070000280194070000190196870000170198770000210200470000210202577300880204620681682017-12-29       2017    bl uuuu     u00u1 u    #d1 aSANTOS, R. R. dos  aEfficacy of oral doramectin as treatment for Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits.  c2017  aThe present study evaluated the efficacy of a single oral dose of doramectin in the control of Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits. Sixteen adult rabbits were selected and distributed in two experimental groups. The treated group received 200 ?g/Kg of oral doramectin and the control group received the same volume of saline solution. The diagnosis of the mites was made with a stereoscopic microscope. Hairs from the dorsal part of the neck, lumbar right, lumbar left, ventral side of the tail and ventral abdomen were evaluated for L. gibbus, and ear wax evaluated for P. ovis. The evaluation of the efficiency and the clinical assessment of the lesions was made in days 0, +3, +7, +14, +21, +28, and +35 after treatment. An efficacy of 75% and 87,5% was observed for L. gibbus in days +3 and +7 after treatment, an efficacy of 100% was observed in days +14, + 21, +28 e +35. An efficacy of 100% for the control of P. ovis was observed following day +7. The clinical lesion score of the control group remained unaltered, except for one animal which conditions worsened during experimentation. In the treated group animals, regression of the lesions was observed following day +3, and on day +21 no signal of infestation by P. ovis was present. None of the animals from the treated group presented secondary collateral effects caused by the doramectin, which proved itself as an optimal alternative for mite control in naturally infested rabbits.  aAvermectins  aDoramectin  aMacrocyclic compounds  aMites  aOryctolagus cuniculus  aPsoroptes ovis  aPsoroptic mange  aRabbits  aAvermectina  aDoramictina  aLeporacarus gibbus  aSarna1 aCOELHO, C. N.1 aNUNES, T. A. P.1 aBATISTA, L. C. de S. O.1 aCORREIA, T. R.1 aSCOTT, F. B.1 aLAGUNA, A. G. V.1 aFERNANDES, J. I.  tPesquisa Veterinária Brasileira, Rio de Janeirogv. 37, n. 1, p. 47-51, jan. 2017.