01762naa a2200205 a 450000100080000000500110000800800410001910000210006024501450008126000090022652010920023565000150132765300130134265300230135565300220137865300140140070000170141470000210143177301040145220659922021-08-09 1998 bl uuuu u00u1 u #d1 aRODRIGUES, G. S. aIn situ assessment of pesticide genotoxicity in an integrated pest management programbII. Maize waxy mutation assay.h[electronic resource] c1998 aThe mutagenicity induced by pesticides applied in an integrated pest management IPM program was evaluated in situ with the maize forward waxy mutation bioassay. Three pesticide application rates were prescribed as follows: (1) Low—no field pesticide spray; (2) Medium—IPM test rate: banded cyanazine plus metolachlor (2.7 kg a.i. and 2.3 l a.i./ha of herbicides, respectively ; and (3) High—a preventative pesticide application program: broadcast cyanazine plus metolachlor (same application rates as above) plus chlorpyrifos (1 kg a.i./ha of insecticide . In general, there was no significant reduction in the genotoxic effects from the high to the medium treatment levels of the IPM program. This suggests that the reduction in pesticide application rates attained with the implementation of the proposed IPM program was not sufficient to abate the genotoxicity of the pesticides. The results indicate that replacing genotoxic compounds may be the only effective remediation measure if concern about environmental mutagenesis were to result in changes in agricultural management. atoxicology aBioassay aIn situ monitoring aMaize waxy pollen aPesticide1 aPIMENTEL, D.1 aWEINSTEIN, L. H. tMutation Research/Genetic Toxicology and Environmental Mutagenesisgv. 412, n. 3, p. 245-250, 1998.