01959naa a2200265 a 450000100080000000500110000800800410001910000190006024500580007926000090013752012320014665000130137865000100139165000110140165000290141265000110144165000100145265300370146265300360149965300090153570000190154470000190156370000210158277300900160320417412016-03-23       2015    bl uuuu     u00u1 u    #d1 aGABARDO, M. P.  aEquine proliferative enteropathy on a brazilian farm.  c2015  aLawsonia intracellularis infection on a horse farm in the Midwest region of Brazil is described. Thirty-nine foals a few days to months old from a herd with 300 horses, experienced diarrhea with variable characteristics and intensities, weight loss, hyperemic mucous membranes and dehydration. In foals 3 to 6 months of age, hypoproteinemia associated with submandibular edema were also common. Intestinal fragments of a 7-month-old foal were sent to an animal disease laboratory for diagnosis. The observed macroscopic lesions were hyperemic serosa, thickening of the intestinal wall with a corrugation, thickening of the mucosa folds and reduction of intestinal lumen. Histological analysis of the small and large intestine revealed enterocyte hyperplasia of the crypts associated with diffuse marked decrease in the number of goblet cells and positive L. intracellularis antigen labeling by immunohistochemistry. Three out of 11 animals of the same property were seropositive for L. intracellularis, demonstrating the circulation of the agent throughout the farm, but none were PCR positive in fecal samples. Based on clinical signs and pathological findings, the diagnosis of equine proliferative enteropathy was confirmed.  aDiarrhea  aFoals  aHorses  aLawsonia intracellularis  aCavalo  aPotro  aEnteropatia proliferativa equina  aEquine proliferative enteropath  aIPMA1 aSATO, J. P. H.1 aRESENDE, T. P.1 aGUEDES, R. M. C.  tPesquisa Veterinária Brasileira, Rio de Janeirogv. 35, n. 5, p. 443-447, maio 2015.