02397naa a2200325 a 450000100080000000500110000800800410001910000190006024501390007926000090021852014190022765000170164665000220166365000200168565000130170565000290171865000150174765000090176265300290177165300250180065300190182565300220184465300260186665300270189265300180191970000180193770000180195570000270197377300710200020383352016-02-24       2016    bl uuuu     u00u1 u    #d1 aBARBOSA, E. H.  aAssessments of motor abnormalities on the grid-walking and foot-fault tests from undernutrition in wistar rats.h[electronic resource]  c2016  aAbstract: This study was designed to verify whether different lactation conditions influenced nervous system development. The authors used motor tasks to verify changes in exploratory activity and muscle strength of weaned rats from different litter sizes and evaluated the applicability of the grid-walking test for assessing motor abnormalities caused by undernutrition. Alterations in litter size during the suckling period perturbed the nutritional status of pups, which exhibited body weight differences between the groups. Large-litter (L) pups showed significant delays in achieving developmental milestones and neurological reflexes compared to the small-litter (S) and medium-litter (M) pups. The S, M, and L group pups exhibited similar exploratory responses and muscle strength. In the grid-walking and foot-fault tests, the L group pups traveled shorter distances and, consequently, had less footsteps. However, the percentages of foot faults in the L group were higher than S and M groups. These results reflect delayed maturation of structures responsible for sensorimotor responses, such as the cerebellum, because much cerebellar maturation takes place postnatally. This is the first study to report that early undernutrition in pups resulted in suboptimal performances on the grid-walking and foot-fault tests and that the former test was sensitive to alterations caused by nutritional deficiency.  aMalnutrition  aMotor development  aNeurophysiology  aReflexes  aDeficiência nutricional  aLactação  aRato  aDevelopmental milestones  aEarly undernutrition  aFootfault test  aGrid-walking test  aNeurological reflexes  aReflexos neurológicos  aSistema motor1 aVALLIM, J. H.1 aLACHAT, J. J.1 aCASTRO, V. L. S. S. de  tJournal of Motor Behavior, Washingtongv. 48, n. 1, p. 5-12, 2016.