01230nam a2200241 a 450000100080000000500110000800800410001910000170006024501790007726001420025630000120039850000200041052003900043065000190082065000220083965000200086165300200088165300230090170000180092470000150094270000180095770000130097520350222020-01-21       2015    bl uuuu     u00u1 u    #d1 aHONGO, J. A.  aPOTIONban end-to-end pipeline for positive Darwinian selection detection in genome-scale data through phylogenetic comparison of protein-coding genes.h[electronic resource]  aIn: INTERNATIONAL CONFERENCE OF THE AB3C, 11.; BRAZILIAN SYMPOSIUM OF BIOINFORMATICS, 2015, São Paulo. Proceedings... [S.l.]: AB3Cc2015  ap. 177.  aX-meeting 2015.  aWe present POTION, an open source, modular and end-to-end software for genome-scale detection of positive Darwinian selection in groups of homologous coding sequences. Our software represents a key step towards genome-scale, automated detection of positive selection, from predicted coding sequences and their homology relationships to high-quality groups of positively selected genes.  aBioinformatics  aComputer software  aGene expression  aBioinformática  aExpressão gênica1 aCASTRO, G. de1 aCINTRA, L.1 aZERLOTINI, A.1 aLOBO, F.